Cinema is an art form that feeds on many different arts and thus can create multifaceted and multi-layered meanings. For this reason, cinema has an approach that can produce original products and, in doing so, can melt different approaches into its own pot. In addition to this, cinema has always interacted with music since its first invention, which gave birth to the concept of film music in the following years, and over time, film music has transformed into a completely different industry outside the cinema industry and has gained a very important position today. Especially when it comes to American Cinema, it can be seen that soundtracks are used in different contexts and meaning transformations in different genres. Hollywood follows a very universal approach in movie soundtracks and reinterprets cult works of different societies within its own structure and in its own contexts around different genres. At this point, this study aims to examine Pyotr Ilyich Tchaikovsky's 1812 Overture (Op: 49) within the framework of different film genres and to analyze the formal and semantic transformation created by the work within the framework of diegetic, non-diegetic and trans-diegetic sound. On the basis of genre, drama, horror-thriller and comedy genres were determined and V for Vendetta (2005), Ready or Not (2019) and Sonic: The Hedgehog 2 (2022) were selected through purposeful sampling method. The main reason for selecting the relevant movies is that they contain outputs compatible with the purpose and argument of the study. The films were categorized into certain categories and analyzed through the descriptive analysis method. As a result, it was observed that the 1812 Overture was used in different genres and films by creating different meanings, and it was observed that this versatile use of this work contributed significantly to the audience's understanding and interpretation of the film.